From singing with Judy Garland in the 1960s to Donna Summer in the 1970s and Tony Bennett in 2006, the singer, 72, has always been up for mixing talents and genres to make musical magic.
Her latest effort – a collection of duets entitled Partners (out Sept. 16) – features some interesting pairings.
The men accompanying the icon?
Everyone from the departed (Elvis Presley) to the dashing (John Legend) and the dear (her son, Jason Gould).
PEOPLE has the exclusive first listen for one of those amazing pairings: her song "I'd Want It to Be You" with country star Blake Shelton, 38.
Listen to the stream for Streisand's romantic duet with The Voice coach.
And check out his cheeky flick at her career (around minute 1:35) – and her cute response.