Camille Cosby's deposition is taking place at the downtown Boston law offices of her attorneys.
The first part of the deposition took place in February at the Springfield, Massachusetts, Marriott, where she was questioned by a lawyer for the accusers.
The deposition is taking place in Massachusetts because the Cosbys are Massachusetts residents, with a home in Shelburne.
Camille Cosby, 72, has repeatedly sought to postpone or end the deposition. A court filing by her lawyers claims lawyers asked her "improper and offensive questions" about her "sexual relations," her political commentary and the 1997 death of the Cosbys' son, Ennis.
"These questions were irrelevant to the issues in this case and plainly were designed to annoy, embarrass and oppress the witness," Camille's lawyers wrote in a motion.
But last week a U. S. magistrate judge ruled that the deposition would continue but that the types of questions would be limited, including a prohibition of questions involving protected communications between spouses.
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"We're not going to have a repeat of some things that happened" during the first day of the deposition in February, U.S. Magistrate Judge David Hennessy said. "I can assure you. We're not going to have questions like, 'Were you asleep when you had sex with your husband.' You will follow the rules."
The plaintiffs in the defamation lawsuit are among about 50 women who claim Bill Cosby drugged and/or sexually assaulted them. Cosby has steadfastly denied all the allegations.
Currently, Bill Cosby, 78, faces charges in a Pennsylvania criminal case. On December 30, newly elected Montgomery County District Attorney Kevin Steele charged Cosby with aggravated indecent assault for allegedly drugging and sexually assaulting former Temple University employee Andrea Constand, now 43, at his Elkins Park, Pennsylvania mansion.
Bill Cosby's criminal attorneys filed an appeal earlier in April to the Pennsylvania Superior Court asking for the case against Cosby to be dismissed. Cosby's attorneys say former Montgomery County District Attorney Bruce L. Castor Jr. promised Cosby he would never be prosecuted in Andrea Constand's case in return for cooperating in her civil suit against him.
The criminal case is on hold until the Superior Court rules on Cosby's motion.