"Once that's starts happening, we're not going to have any more protesters, folks," Trump said.
Trump's comments came while appearing at a Kansas City, Missouri, theater during an event that was interrupted more than a dozen times, according to CNN.
"I hope they arrest these people because they're really violating all of us," Trump, 69, continued. "They deserve to be arrested."
"I'll file whatever charges you want," he said. "If they want to do this ... we're going to go strongly for your arrests."
"We're going to take our country back from these people," Trump said, according to ABC News. "These are bad, bad people."
These "big arrest marks" for the protestors, Trump said, would "ruin the rest of their lives," according to CNN.
"I hope these guys get thrown into a jail. They'll never do it again. It'll destroy their record. They'll have to explain to mom and dad why they have a police record and why they can't get a job," Trump said. "And you know what? I'm going to start pressing charges against all these people, OK? ... The only way that we're going to stop this craziness is if we press charges. Because then their lives are going to be ruined."
Christopher Smith / Kansas City Star / TNS via Getty
Some protestors threw "objects," according to a tweet from Kansas City Police Chief Darryl Forté.
But the "majority of people exercised their rights peacefully," Kansas City police tweeted.
The Saturday night event capped 24 hours of intense attention on Trump's rallies and his occasionally aggressive rhetoric therein – and the protests, demonstrations, and large groups of supporters that his bold, controversial political stances draw.
Jabin Botsford / The Washington Post via Getty
A Trump supporter was charged with assault last week after video showed him sucker-punching a protestor at a rally in Fayetteville, North Carolina, according to the Washington Post.
Protestors have also previously been arrested at Trump events, including at an event in St. Louis on Friday, according to CBS News.
Trump's campaign canceled a Friday night appearance at the University of Illinois at Chicago, citing safety concerns after hundreds of protestors attended the public event. Tensions flared following the cancellation, as attendees feuded, sometimes physically, according to photos and video.
Other presidential candidates quickly condemned Trump's "divisive" rhetoric as key in these events.
Trump told CNN's Don Lemon after the Chicago cancellation that "I hope that my tone is not that of causing violence."
Later on Sunday, Trump responded to Sen. Bernie Sanders' comments about the rally protests, accusing the protesters of being supporters of the liberal Democratic candidate – and that they are encouraged to attend Trump's rallies to protest.
"Bernie Sanders is lying when he says his disruptors aren't told to go to my events," Trump wrote. "Be careful Bernie, or my supporters will go to yours!"
Bernie Sanders is lying when he says his disruptors aren't told to go to my events. Be careful Bernie, or my supporters will go to yours!— Donald J. Trump (@realDonaldTrump) March 13, 2016
Appearing Saturday in Dayton, Ohio, he was briefly surrounded by Secret Service after a man allegedly moved toward the stage.
(The man was subsequently arrested and charged with disorderly conduct and inducing panic, Dayton International Airport Police Chief Mike Etter told NBC News.)
That incident appeared to jar Trump, but the Republican presidential front-runner bounced back, telling the crowd, according to the Dayton Daily News, "Is anything more fun than a Donald Trump rally?"