The Wolverine star took to Instagram on Monday to share a bandaged post-op photo of himself.
"An example of what happens when you don't wear sunscreen. Basal Cell. The mildest form of cancer but serious, nonetheless. PLEASE USE SUNSCREEN and get regular check-ups," Jackman, 47, wrote in the caption.
Jackman's rep tells PEOPLE the procedure was a success.
"He had a basal cell removed [Monday] morning. The margins are clear and he's fine."
This certainly isn't the first time the actor has used social media to warn against skin cancer. This marks his third post-op photo in three years, and fourth procedure on his nose.
The actor was first treated for basal-cell carinoma in November 2013. He posted a photo online, saying his wife, Deborra-Lee Furness, had encouraged him to get the "mark" checked. He posted a second photo in May 2014.
Jackman opened up to PEOPLE about his battle with skin cancer last year, during which he admitted he was shocked to learn of his diagnosis.
"It's always a bit of a shock just hearing the word 'cancer,' " he said. "Being an Australian it's a very common thing. I never wore sunscreen growing up so I was a prime candidate for it."
Along with the spot on his nose, he has also had skin cancer cells removed from his shoulder.
Basal-cell carcinoma is the single most common form of cancer, according to the Skin Cancer Foundation. Almost 3 million cases are diagnosed in the U.S. each year. It almost never spreads beyond the lesion site but can be disfiguring if allowed to grow.
"I go every three months for check-ups," he said. "It's the new normal for me. My doctor says I'll likely have more, and if that's your cross to bear in life, you should be so lucky."