"Amy is so sexy and so gorgeous and so delicious," Seinfeld, 44, told PEOPLE while promoting her line with HSN. "She's a woman that every man in the room wants to be around, and she's the woman everyone wants to be friends with. What her body looks like – which is drop dead gorgeous – is irrelevant. Whatever she's doing and whatever she looks like I think is phenomenal. "
Seinfeld – who recently went on a tropical vacation with the comedian – also spoke out about the use of the term "plus size" to describe Schumer, who is a size 8.
"The fact that a size 8 is considered plus size is pretty scary," she said. "We need to reconsider our role models if that's the case."
Schumer, 34, took to Instagram earlier this month to slam Glamour for labeling her plus size.
"I think there's nothing wrong with being plus size," she wrote. "Beautiful healthy women. Plus size is considered size 16 in America. I go between a size 6 and an 8. @glamourmag put me in their plus size only issue without asking or letting me know and it doesn't feel right to me. Young girls seeing my body type thinking that is plus size? What are your thoughts? Mine are not cool glamour not glamourous."
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"First off, we love Amy, and our readers do too – which is why we featured her on the cover of Glamour last year. The cover line on this special edition – which is aimed at women size 12 and up – simply says 'Women Who Inspire Us,' since we believe her passionate and vocal message of body positivity IS inspiring, as is the message of the many other women, of all sizes, featured. The edition did not describe her as plus-size. We are sorry if we offended her in any way."
Reporting by SHARON CLOTT KANTER