While in Cambridge on Saturday evening to be honored by the Harvard Lampoon, Harvard University’s humor magazine, Fallon tripped and fell while holding a bottle of Jaegermeister, and subsequently made a trip to Massachusetts General Hospital.
A source tells PEOPLE that "everything is totally fine" and "It was all part of the celebration in the street and some random girl kneeled down in front of him abruptly as he was turning around and he tripped over her because he didn't see her."
Pictures posted on social media reveal he hurt his right hand, just four months after he badly injured his left hand after a fall in June.
Looking dapper in a black tuxedo, the Tonight Show with Jimmy Fallon host was on campus to be honored with the Elmer Award for Excellence in Humor, which is the first time the coveted prize has been awarded this century.
"Jimmy went to the ground, and everybody asked if he was OK," said one parade-goer. "He said he was fine."
One fan managed to catch Fallon’s tumble on video and posted it to Instagram.
While the Cambridge Police were able to help Fallon back up, the funny guy soon took off in his limo and headed straight for the hospital.
"A guy and a guy got out of the limo, and went in before him for like five minutes," said an autograph seeker. "They came out, waved to the car, Jimmy got out, and they all walked into Mass General."
Fallon, himself, spoke out about the new injury through social media on Sunday.
"Nothing that a few band aids couldn't fix," he wrote alongside a photo of his right hand, which had two band-aids on it.
Courtesy Jimmy Fallon
Later, Fallon was snapped in an Instagram partying with the rest of the Lampoon squad – with his hand heavily re-bandaged.
Fallon nearly severed his finger in a fall at his home this summer.
Earlier in the afternoon, the funnyman hung out at the Hong Kong Restaurant, a popular bar in the Harvard Square area, where he drank Scorpion Bowls with several tux-clad Harvard students.
"He was waving at people, and taking selfies with girls," said the same autograph seeker. "Everybody would scream every time he stood up."