John Stamos, Zendaya, Heidi Klum, Keke Palmer and Bethany Mota are all set to appear (their exact participation is being kept under wraps!) at the annual slime-fest, PEOPLE confirms exclusively.
Blake Shelton – who released his new single "Came Here to Forget" on Tuesday and is nominated for favorite male singer – will host what's sure to be a hilarious show.
"I've been on countless stages throughout my life, but none have promised the madness, excitement and endless slime as Nick's Kids' Choice Awards, which is undoubtedly the ultimate party for kids," the Voice coach told PEOPLE in November. "There is only one team here, and it's Team Kids' Choice so bring it on Nickelodeon!"
Voting for the awards show – which airs live on March 12 at 8 p.m. ET – is currently open on Nick.com.