In response to a request for comment from 20/20, Holmes issued the following statement, which was provided to PEOPLE by her publicist:
"I regret having upset Leah in the past, and wish her only the best in the future," Holmes says.
VIDEO: Former Scientologist Leah Remini Shows Support for Scientology Doc
Holmes, who divorced Tom Cruise – one of Scientology's most famous faces – after nearly six years of marriage in 2012, has never spoken out about Scientology or her ex-husband's involvement in the church.
"In response to an email sent from the producers or fact-checkers from 20/20 asking a plethora of questions, we supplied no answers and instead gave only a one-sentence statement in response," Holmes' publicist told PEOPLE. "Katie is not making an appearance on the special, nor is she discussing Scientology, or her former marriage, and this quote was provided through her publicist."
"For any outlet to suggest otherwise is misleading; I would think Leah and the book stand on their own, and don't need to trade off Katie Holmes for people to tune in."
In the 20/20 interview, Remini said that after Holmes' wedding to Cruise, Holmes filed a "Knowledge Report" with the Church of Scientology criticizing Remini's behavior at the wedding. Holmes did not comment to 20/20 about the alleged report.
"Being critical of Tom Cruise is being critical of Scientology itself," Remini said on 20/20. "You are a person who is anti the aims and goals of Scientology, you are evil."
She claimed that two high-ranking officials were present in the home to monitor the lesson, along with Holmes (who was dating Cruise at the time).
Remini, 45, said that when she commented on Cruise kissing Holmes throughout the night, she was written up and reported to the church.