Pope's Relatives Killed in Road Accident: Report
08/19/2014 AT 09:30 AM EDT
The accident occurred in the Cordoba area, about 360 miles northeast of Buenos Aires.
Reports give the name of the nephew as Emanuel Bergoglio. The children were 2 years old and and 8 months old.
Bergoglio's car reportedly collided into the rear of a truck.
The Holy Father was "profoundly saddened" by the news, his spokesman Francesco Lombardi said, according to the BBC.