Age at high-risk diagnosis: 37
After tests revealed she had a high risk of developing breast cancer, Jolie quietly underwent a double mastectomy in February, she told the New York Times in a May 14 op-ed article. "I wanted to write this to tell other women that the decision to have a mastectomy was not easy. But it is one I am very happy that I made," writes the mother of six. "I can tell my children that they don't need to fear they will lose me to breast cancer."