Over the past decade, ER
's favorite doc became a movie star and an Oscar winner (for 2005's Syriana
). Starring in 20 films and directing three, Clooney still found time to visit Darfur refugee camps. Now, with his girlfriend Elisabetta Canalis at his side and Oscar buzz for his Up in the Air performance, there's no sign of slowing down—except for a few grey hairs. "I'm old," Clooney, 48, told The Daily Telegraph
. "I'm comfortable with getting older because it's better than the other option, which is being dead."