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RIDICULOUSLY PHOTOGENIC GUY

This meme became so popular that its star, Zeddie Little, who became the poster boy for perfection, made an appearance on Good Morning America.

Botched Ecce Homo Painting

A Spanish citizen's swirly-faced fail at restoration made its way into other works of art like The Scream and Mona Lisa.

MCKAYLA IS NOT IMPRESSED

This expression from the U.S. gymnast became the go-to way to show displeasure.

OVERLY ATTACHED GIRLFRIEND

An overly ardent Justin Bieber fan became the face of emotional clinginess.

TEXTS FROM HILLARY

Imagined e-missives from the Secretary of State to Ryan Gosling, Oprah Winfrey and countless others.

Angelina Jolie's Leg

The superstar's dramatic pose and sky-high slit on the Academy Awards red carpet inspired multiple parodies and its own Twitter feed, @AngiesRightLeg.

NASA MOHAWK GUY

Engineer Bobak Ferdowsi-spotted during coverage of the Mars rover landing-became such a sensation even President Obama joked, "I've thought about getting a mohawk myself."

Dancing Prince Charles

While visiting the Channel Islands as part of the Diamond Jubilee, Prince Charles let loose with a royal jig and launched himself into meme-hood. His highness was subsequently Photoshopped into doing everything from a disco jig to chasing a "chubby bubble girl."