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The collection, scheduled for November, will feature interviews with Winfrey as she reflects on her career and her show, scenes from backstage on Oprah, as well as some of the show's most poignant moments.
"Every show you'll see here holds such profound meaning for me," Winfrey said.
In addition, Winfrey's proceeds from the discs' sales will be donated to her charity, Oprah's Angel Network. Since it was created in 1998, the Angel Network has raised more than $30 million for various nonprofit organizations, Reuters reports.
About 30 million people tune into Oprah each week, according to Nielsen reports. It has been the No. 1 talk show for 18 consecutive seasons.
