Kathy Griffin Files for Divorce
Her rep declined to comment, but the divorce papers cited irreconcilable differences.
The couple have no children.
Griffin and Moline wed in Hollywood in February 2001, as maid of honor Brooke Shields and guest Camryn Manheim looked on.
The heavy metal band Night Ranger's "Sister Christian" played as Griffin was given away by her dad, John.
"Matt's mom bought the Martha Stewart wedding book," Griffin told PEOPLE at the time. "And I kept saying, 'You're not going to have to crack that book open.'"