10/14/2006 at 11:00 AM EDT
Actress Mel Harris, best known for her role as Hope Murdoch Steadman on the hit 1980s TV show thirtysomething, filed for divorce from her investment-banker husband of five years, Mike Toomey, in Los Angeles Superior Court on Oct. 3, PEOPLE has learned.
In the court filing, Harris, 49, cited irreconcilable differences and requested that the "court's jurisdiction to award spousal support" to her husband be terminated. The couple has been married since 2001.
Harris and Toomey have no children together but the actress (most recently seen in guest-starring roles on House and Cold Case) has a son, Byron, 22, and daughter, Madeline, 16, from previous marriages.