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Hefner, Larry King Weigh in on Anna Nicole Death | Anna Nicole Smith, Hugh Hefner
• "I'm very saddened to learn about Anna Nicole's passing. She was a dear friend who meant a great deal to the Playboy family and to me personally. My thoughts and prayers are with her friends and loved ones during this difficult time."
Playboy founder Hugh Hefner, in a statement to CNN

• "She was a special person; she was an unusual person. She was genuine; she was funny; she had some class. I feel very, very sorry for everybody concerned, but mostly for that little girl."
Larry King

• "She had something magic ... This is a very tragic and sad day ... Personally I feel she did not recover from the loss of her son Daniel who was the love of her life."
Paul Marciano, CEO of Guess jeans, in a statement to CNN

• "PETA is extremely upset by the news of Anna Nicole Smith's untimely death. She was a great friend to animals and used every opportunity to speak out against senseless cruelty. We always thought Anna Nicole was a perfect fit for PETA because, just like us, she not only hated cruelty to animals and loved her dog ... It is a tragedy when anyone passes away before their time, but with Anna Nicole, animals have lost a true hero and PETA has lost a good friend. We will miss her."
People for the Ethical Treatment of Animals, in a statement

• "E! Networks is deeply saddened by the tragic news of Anna Nicole Smith's death. Our thoughts are with her family and loved ones."
E!, which broadcast The Anna Nicole Show from Aug. 2002 - Feb. 2004

• "Today, Anna Nicole Smith's grief-stricken and tumultuous personal life came to an end. Anna came to our Company as a customer, but she departs it as a friend .... Anna knew both the joy of giving life, and the heartache of losing a child. We pray that she is granted the peace that eluded her more recent days on earth, and that she finds comfort in the presence of her son, Daniel."
– Alex Goen, CEO of Trimspa, for whom Smith was a spokesmodel, in a statement

Visit PEOPLE.com for continued coverage of Anna Nicole Smith as the tragic story continues to develop.