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"It is, in fact, a drug," the former View co-host, 45, said Sunday at New York City's BookExpo America, the publishing industry's annual national convention.
She added that she'd seen some of her fellow celebrities be so transformed by fame that they reminded her of crystal meth users, the Associated Press reports.
Plugging her upcoming memoir, Celebrity Detox, due out in the fall, O'Donnell also addressed her trials this season on The View, which she left two weeks ago.
Her on-air sparring partner, Elisabeth Hasselbeck, should have nothing to worry about when the book comes out: O'Donnell promised the memoir will not be "vindictive" or "mean-spirited," although it will cover her tumultuous stint on The View.
In the wake of her exit from the show, she said, "We've had to change the [book's] epilogue." She then quipped that her next career step would be "auditioning for The Apprentice."
In reality, O'Donnell will go on the road with Cyndi Lauper's True Colors Tour, followed by her book release.
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