12/11/2006 at 01:00 AM EST
"He has a long way to go," says Pickens of his character, chief of surgery Richard Webber, trying to save his marriage after years of late hours (not to mention an affair). "He's human. He is such a human." Pickens doesn't have to worry about Gina, his wife of 22 years, getting annoyed at his work schedule. "God bless her, she's a big fan of the show," says Pickens, 54. "I'll come home and say, 'Oh, we have this or that coming up' and she'll say, 'I don't want to know!' We'll watch it together."