"I would love to be Oprah – for just one day," the actress tells Harper's Bazaar in the magazine's 140th anniversary issue.
Aniston and Winfrey have been pals for some time, and last year the talk show host shot down rumors that she was planning a $1 million wedding for the actress and her then-boyfriend, Vince Vaughn.
Continuing the line of questioning about Aniston's fantasy life, she's asked what she'd do if she worked for the government. "I'd be a spy. A very glamorous spy who plays poker and lives in Monaco," she says. "And has affairs with Daniel Craig."
Talking more seriously about her life as one of the most recognizable faces in the world, Aniston, 38, recounts once walking 40 blocks in New York City without anyone noticing her.
"If you can get away from the paparazzi and they don't know where you are, you can actually walk, walk, walk," Aniston says of the city where she is contemplating living again.
"I don't know, I'm just tired of Los Angeles," she tells the magazine, which goes on sale Oct. 23. "In New York, you're not just in that same car, looking at that same dashboard, driving down the same street."
As for dealing with what both critics and the public think about her, she says she no longer pays attention to it. "I used to care a hell of a lot more about what people said or thought. But that had to change when my life was under a microscope being scrutinized and my personal life was being talked about," she says. "You have to go, 'This is not acceptable in any way,' whether it's about me personally or in business, success versus failure."
Still, Aniston expresses surprise at her own massive success on television – and isn't afraid to poke a bit of fun at it.
"I don't think anybody thought Friends would become what it did," she says. "It's all good, though. It's nothing but blessings," she says. "But seriously, who actually dances in a fountain?"