Kennedy's statement went on to say that the operation would be followed by chemotherapy and radiation at Massachusetts General Hospital in Boston, reports Reuters. The senator checked into Duke on Sunday.
The surgery, to be performed by Dr. Allan Friedman, chief of neurosurgery at Duke, was scheduled for around 9 ET and was expected to last about six hours. The senator, 76, said he anticipated remaining hospitalized at Duke for about a week.
The condition of Kennedy, Massachusetts's Democratic senator for the past 46 (when he succeeded his brother, John F. Kennedy, after JFK went on to the White House), has prompted a wave of shock and sympathy from both sides of the political aisle.
"I am deeply grateful to the people of Massachusetts and to my friends, colleagues and so many others across the country and around the world who have expressed their support and good wishes as I tackle this new and unexpected health challenge," Kennedy said.
"After completing treatment, I look forward to returning to the United States Senate and to doing everything I can to help elect Barack Obama as our next president."
More Photos: See Ted Kennedy Covers