Sarah Silverman and Jimmy Kimmel
Jordan Strauss/WireImage; Seth Wenig/AP
08/01/2008 AT 10:15 AM EDT
No joking matter?
Sarah Silverman – who has been silent since her split
with Jimmy Kimmel last month – briefly addressed the break-up during her stand-up performance Thursday night.
"Did someone tell you I'm going through a hard time?" Silverman, 37, jokingly told an audience of 300 at West Hollywood's Largo at the Coronet. (A few sympathetic cries came from the front of the crowd.)
But the edgy comedienne – who famously called Britney Spears
's two sons "adorable mistakes" – quickly moved on and avoided jokes about Kimmel, 40, and relationships in general.
In the 15-minute set, Silverman instead joked about Barack Obama, Kanye West
, a 13-year-old relative and a home-taped radio show from a writer on her TV show, The Sarah Silverman Project
Wearing a green shirt, jeans and her hair in pigtails, Silverman was followed by Jeffrey Ross, who practiced material for Sunday's Comedy Central Roast of Bob Saget.
Silverman and Kimmel – who were heralded as PEOPLE's Funniest Couple Alive
this year – dated for five years before their surprise split.