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The 14-year-old son of the star's cousin Fiona Bonham Carter was said to be the youngest victim, while his mother, 51, escaped with a broken collar-bone and his older brother suffered whiplash.
Three others, including the boy's maternal grandmother, Brenda Bonham Carter, his step-grandfather and aunt also died, the UK's Foreign Office has confirmed.
Their vehicle reportedly lost control and overturned on a road near the Welgevonden game reserve.
The UK rep for Bonham Carter, who gave birth to her second child– Nell – in December, had no comment.
