09/13/2008 AT 11:05 PM EDT
Kathy Griffin might need to consider adding another member to her staff just to carry around her Emmy awards.
The comedian won her second Emmy on Saturday, picking up the trophy for best reality program for her Bravo hit My Life On the D-List.
And, true to form, she delivered another memorable – and bleepable – acceptance speech.
"Well, well, well! Here we go again, f-----ers," Griffin said, gamely accepting the award at the Creative Arts Emmys held at the Nokia Theatre in Los Angeles.
"I'm not going to tell anyone to suck it," she said, referencing her speech from 2007 in which she infamously told Jesus to "suck it." "I would make love to this thing if I could."
On her way into the award show, the comedian, in a dress by Rebellion Dogs, told PEOPLE she was "beside myself with glee and nervousness." The comedian also joked about her competitors. "I want to take down Antiques Roadshow
once and for all," she said. "I'm tired of those guys just running the world."
Griffin was also nominated for a stand up comedy special, though she lost the award to Don Rickles, with whom she is presenting an award at the Primetime Emmys next weekend. "Can you believe it? I'm in heaven," she said of presenting with Rickles. "It's what should have been the Obama/Hillary ticket of comedy. I'm very excited about that and being with him and standing next to him. I just love him."
Griffin was not the only salty celebrity to collect an award at the ceremony hosted by Neil Patrick Harris and Sarah Chalke. Sarah Silverman won an Emmy for her parody music video
"I'm F----- Matt Damon."
Also honored at Saturday's ceremony: Cynthia Nixon, who was named best guest actress in a drama for her role as a psychopathic mother on NBC's Law & Order: Special Victims Unit
and Tim Conway, who was named guest actor in a comedy series for 30 Rock.
And for the tenth year in a row, The Simpsons
was named the best half-hour animated show.
The Creative Arts Emmys will air on Sept. 20 on E!, the day before the Primetime Emmy Awards will air live on ABC.
Reporting By Elaine Aradillas, Jed Dreben and Cynthia Wang