As determined by the Hollywood Foreign Press Association, Winslet, along with Mickey Rourke, Colin Farrell, Happy-Go-Lucky's Sally Hawkins, the late Heath Ledger, Slumdog Millionaire, and Woody Allen's Vicky Cristina Barcelona were the top winners in the film categories.
The HBO miniseries John Adams, AMC's Mad Men and NBC's multiple-winner 30 Rock took TV honors.
Winslet Grows TearfulApologizing to her sister nominees for best actress Anne Hathaway, Angelina Jolie (whose name she momentarily forgot), Meryl Streep and Kristin Scott Thomas, Winslet grew progressively tearful as she delivered her thanks "off the cuff."
"Leo," she said, looking at her costar in the film, her long-ago Titanic screen lover Leonardo DiCaprio, "I am so happy I can stand here and tell you I love you, and have for 13 years."
She also thanked her husband Sam Mendes, who directed Revolutionary Road, for putting her and DiCaprio "through hell every day."
Mickey Rourke – whose star rose in the '80s only to flame out – was named best dramatic actor for The Wrestler, and acknowledged, "This has been a really long road back for me."
He also suggested he might be better off if Robert Downey Jr. came up and delivered his speech for him, though Rourke ultimately proved both eloquent and colorful.
Top PictureSlumdog Millionaire, about a young man in India whose arduous life unfolds during his stint on his country's version of Who Wants to Be a Millionaire, was named best dramatic picture. It also took home Globes for its director Danny Boyle, as well as for its original score and screenplay.
Letty Aronson, who produced her brother Woody Allen's Vicky Cristina Barcelona, accepted the top comedy picture Globe on behalf of her notoriously introverted sibling.
The HBO historical drama John Adams swept the TV categories, with Globes going to leading actor Paul Giamatti, actress Laura Linney, supporting actor Tom Wilkinson and producer Tom Hanks, for best miniseries.
Mad Man was named best dramatic series.
Alec Baldwin, who won for best actor in a comedy series for his huffy network exec on NBC's 30 Rock, thanked show creator, writer and his costar Tina Fey three times. He also thanked his daughter Ireland, "who makes me laugh when I'm home."
Colin Farrell appeared genuinely surprised to be named best actor in a comedy for In Bruges. He thanked his director, Martin McDonagh, for ignoring his advice to cast someone else in his role.
While Brad Pitt's The Curious Case of Benjamin Button and Angelina Jolie's Changeling were shut out of the awards, the duo received plenty of attention – from one another. Throughout the three-hour ceremony in the international ballroom of the Beverly Hilton Hotel, the pair were openly affectionate.
For the full list of winners, click here.