Picks and Pans Review: Samantha Who's Melissa McCarthy the Perkiest Pal on TV

updated 01/19/2009 at 01:00 AM EST

originally published 01/19/2009 01:00AM

• As Sam's friend Dena, the 38-year-old costar of the ABC sitcom won't even let dog slobber dim her cheer.

ARE YOU AS REMOTELY PERKY AS YOUR CHARACTER DENA?
I tend to be spazzy like her. I do a million things at once—to my husband's [actor Ben Falcone] chagrin. It doesn't help that I come home from working 14 hours like I've been pounding coffee all day.

DO YOU BOND WITH THE SHOW'S NEWFOUNDLAND DOGS?
They're the most sweet, lumbering dogs, but they drool like crazy. I have a kid [Vivian, 1], so their slobber is nothing compared to dirty diapers.

HOW IS STAR CHRISTINA APPLEGATE [WHO BATTLED BREAST CANCER] DOING?
She's a powerhouse and continues to be strong and well. Never did she stop to say, "Poor me." She's a huge inspiration.

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