02/28/2009 AT 06:30 PM EST
From Traveling Pants
to a new white coat: Alexis Bledel is set to guest-star on the two-hour series finale of ER
, PEOPLE has learned.
Bledel, who starred in the Sisterhood of the Traveling Pants
movies and played daughter Rory for seven seasons on TV cult favorite Gilmore Girls
, will scrub in as new intern Dr. Julia Wise.
The final episode will mark the 27-year-old's only appearance on the show, which is ending its run April 2 on NBC.
Bledel joins a list of stars scrubbing into ER
for the farewell season, including George Clooney
, whose episode will air March 12