04/06/2009 at 01:00 AM EDT
>• On April 2, NBC's hit medical drama signs off after 15 years. PEOPLE visited the set one last time to take the pulse of the cast and crew as they said goodbye.
Like a doctor who refuses to give up on a flatlining patient, John Stamos remains in denial about ER's demise. "It's silly to end this," he says, shaking his head as he surveys the drama's set. "This show could go on forever." But on April 2, the NBC drama will go off the air for good. When PEOPLE visited the ER set on one of its final shooting days, the cast and crew were feeling nostalgic—"We're emotional, but still having fun," says series finale director Rod Holcomb—yet already scouting the set for souvenirs. "The whole show consists of us running through doors," says Stamos. "I gotta have one." And on that final episode, look for more of a whimper than a bang: "I didn't want the place burning down," says executive producer John Wells. "The business of the ER is ongoing, like it was the day we walked in."