Sandra Bullock

UPDATED 12/28/2009 at 01:00 AM EST Originally published 12/28/2009 at 01:00 AM EST

Whether getting naked for laughs with Ryan Reynolds in The Proposal or playing den mother to a homeless high school football player in The Blind Side, Bullock, 45, is once again on a hot streak. The two hits have raked in more than $300 million and reminded audiences how adept Bullock has always been at switching gears between drama and comedy—as her turns in 2005's Academy Award-winning Crash and in the Miss Congeniality comedies also attest. But these days Bullock (happily married to TV host Jesse James since 2005) is also getting Oscar buzz. "Men love her and women love her, and that's extremely hard to pull off," says Reynolds. "To know her is to love her, but also to just watch her is to love her."

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