"It's two very successful people, and it's not easy," Jenner, 60. told the radio show Kidd Kraddick in the Morning about his stepdaughter and her NFL star beau. "I hope for the best … I love Reggie. Reggie's a great guy. I love Kim. She's just a super sweet, great human being."
Kardashian, 29, and New Orleans Saints runningback Bush, 25, recently decided to step back from their relationship, in part because Bush has been struggling with Kardashian's demanding schedule.
On whether the on-again, off-again pair would stay together, Jenner – who along with Kardashian, his wife Kris and his other children and stepchildren star in the reality show Keeping Up with the Kardashians – said, "I try not to pry into what they're doing. I really haven't talked to her about this … who knows what's going to happen."