Half of Hollywood Boulevard was shut down, and hundreds of fans erupted in pandemonium as the couple arrived at Grauman's Chinese Theatre – Jolie in an Emporio Armani dress and Ferragamo shoes – and greeted fans before heading inside for the screening.
At the afterparty, the couple held court in a special area, flanked by a phalanx of security, in the middle of Hollywood & Highland's Grand Ballroom. One guest of honor was Jolie's father, Oscar winner Jon Voight, 71, who looked thrilled as Pitt chatted affectionately with him throughout the evening and he shared a hug with his daughter.
The inner circle got a boost of energy when they were joined by Quinton Aaron, 25, the actor who played Michael, the son of Sandra Bullock's character, in The Blind Side. Both Jolie, 35, and Pitt, 46, spent time enthusiastically chatting with him, and Aaron became the life of the afterparty, taking dozens of photos with fans who approached him.
A few feet away from the Jolie-Pitts was another special area set up for costar Liev Schreiber and his partner, Naomi Watts. Schreiber, 42, who has two small boys with Watts, told PEOPLE that he bonded with Jolie over parenting during the shoot.
"I think we're both in that place with our kids where they're really amazing, right around 3 years old, when all the language starts to come out of them," Schreiber said. "It's a very exciting period in someone's life, both the child's and the parent's, and it was fun to bond over that."
Jolie and Pitt left at around 11 p.m. after another big day in their hectic lives.
"What's amazing about [Jolie] is the amount of things going on in her life and how calm she is in the middle of them," producer Lorenzo di Bonaventura told PEOPLE. "She's an unbelievably committed mom, and she's an unbelievably committed actress, and on human rights ... it's a whirlwind going on around her, and in the middle of it she's as calm as can be."
With additional reporting by MARY GREEN