"Ironically, with all this, 'We're now more connected than ever with technology,' I don't think we've ever been farther apart," the actress, 35, tells Nylon's August/Denim issue. "I think it's bulls---."
Technology and social media make everyone feel "more connected," she says, "but [we're now] weirdly disconnected."
Something else she can't stand: Trying to be someone she's not.
"You have to not pretend to be perfect, because that's not only boring as [expletive], but it's just not real," she says.
"I just really want to be true to myself," adds Barrymore. "That's essential in life. I would never be able to put on a charade. I would totally [screw] it up."
As for her on-again, off-again beau Justin Long, the actress couldn't have had a better time working with him on their upcoming film Going the Distance – in which he goes nude.
"It's funny because usually it's the girl who's naked," she says. "I was like, 'That's right, bitch. The tables are turned!' "