Lowe, 42, and film producer Kim Painter, were married Saturday in front of family and a small group of friends in an oceanside ceremony at Terranea Resort in Los Angeles.
Chad's brother Rob Lowe was best man. The couple's 15-month old daughter Mabel served as ring bearer.
Lowe and Painter began dating in January 2007. They welcomed Mabel in May 2009 – the first girl born into the Lowe family in nearly four generations.
Heidi Mayne of Red25 Events organized the wedding.
Reporting by JULIE JORDAN