"My advice for her is to get more sleep than the actors,” Eastwood, 80, told PEOPLE at the Toronto International Film Festival premiere of his latest, Hereafter. "And to have good management – know what you want and know what you are looking for and go after it."
Jolie, 35, is also producing the film and writing the screenplay for the sweeping love story set during the Bosnian War. Despite the many hats she'll have to juggle, Eastwood says he has no doubts Jolie will succeed – and create a masterpiece.
"She's a very intelligent gal," says Eastwood. "I know she'll do great. I haven't discussed it with her on this particular occasion, but I know she'll be tough to stop. She has a great work ethic and she's very smart. I'm looking forward to seeing what she does."