The typically lovey-dovey couple, weathering a storm amid a tabloid report that Kutcher had an affair, made an appearance at the Clinton Global Initiative conference in New York to launch their "Real Men" campaign against child sex slavery.
Holding hands and wearing their wedding bands, the two stood close together at the podium while discussing the DNA (Demi and Ashton) Foundation's mission to "create a trafficking-free Internet."
Moore, 47, and Kutcher, 32, who will mark their fifth anniversary on Friday, were attentive to each other throughout the press conference – with the actress clasping her husband's hands on her lap when they were seated.
Asked what can be done to end sex trafficking, an emotional Kutcher, whose celeb pals such Ben Stiller and Snoop Dogg have already given their support for the cause, told reporters, "People can get off their ass and start acting appropriately."
Reporting by MARY PARK