The actor, 48, was convicted in April 2008 of three misdemeanor counts of willful failure to file income taxes.
After two years of unsuccessful appeals, Snipes accepted his fate and, on Thursday, turned in his street clothes for a prison uniform at the McKean Federal Correctional Institution in Lewis Run, Pa.
Snipes will eventually settle into the adjacent minimum security prison camp, according to Federal Bureau of Prison spokesman Edmond Ross, ABC News reports.
Ross added that Snipes, who surrendered around noon on Thursday, was processed "without incident" and will be assigned a bunk after he completes inmate orientation.
Snipes was asked by CNN's Larry King if he was nervous about going to prison and admitted his trepidation about doing time.
"I think any man would be nervous," Snipes said. "Given the length of time that they are suggesting that I be away from my family, away from my profession, away from my ability to provide for my family and for those who have depended upon me to contribute to society ... I think anyone would be nervous about that."