The actor "has voluntarily entered an undisclosed rehabilitation center today," the actor's rep says in a statement Friday. "He is most grateful to all who have expressed their concern."
News of Sheen, 45, seeking treatment comes one day after the actor was rushed to a Los Angeles hospital citing severe abdominal pain.
Sheen's highly successful sitcom, Two and a Half Men, is going on hiatus due to the star's decision to enter rehab, according to a statement from CBS, Warner Bros. Television and executive producer Chuck Lorre.
"We are profoundly concerned for his health and well-being, and support his decision," they say in the statement.
In October, Sheen was involved in an hotel trashing melee that allegedly involved porn actress Capri Anderson, but no criminal charges were filed.
Last August, Sheen pleaded guilty to misdemeanor assault and was sentenced to rehab after a Christmas Day fight with ex-wife Brooke Mueller. He completed three months of probation in that case.