Penélope Cruz: Johnny Depp Is a Potty-Humor Prankster

03/25/2011 AT 11:15 AM EDT

He's known for his high-concept collaborations with filmmaker Tim Burton, but Johnny Depp isn't above classic, slapstick humor – just ask Penélope Cruz, who's been the target of Depp's "fart machine."

"He fooled me once when we were doing Blow," Cruz, 36, told Jimmy Kimmel Thursday night on Jimmy Kimmel Live of her first time on set with Depp. "I was doing a very dramatic close-up, and he kept making that sound with the machine … I was just thinking, 'I hope they're not thinking it's me.' "

That was 10 years ago. Now that the duo are reuniting on-screen for the latest installment of Pirates of the Caribbean, which arrives in theaters May 20, Cruz says not much has changed – except for that machine.

"When I met him 10 years ago, he had a plastic [fart machine], and now, 10 years later, he has one with a remote control."

Depp, 47, leaves her alone now, the new mom says, opting to get his jollies off pranking director Rob Marshall and producer Jerry Bruckheimer. Jokes aside, she says, "I only have great things to say about [Depp]."

"He's really one of the most kind and genuine people that I have ever met," she says. "And he's so funny – I guess people know how funny he is."

She adds: "I love working with him."

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