While a rep for Los Robles Hospital & Medical Center tells PEOPLE that Locklear, 50, was discharged from their hospital Friday evening, leaving in the care of her family, she was reportedly "out of control" when her sister dialed 911 night prior, according to Entertainment Tonight.
"Heather became a different person on drugs," a source tells the show, adding that Locklear, who was spotted on Tuesday night at an L.A. Lakers game, may be heading into rehab shortly.
Locklear's rep hasn't immediately commented on the actress's condition, but this isn't the first time 911 has been called on behalf of the actress.
In March 2008, her doctor called 911 reporting that she was suicidal. Months later, the actress sought treatment at an Arizona facility for anxiety and depression.
"Heather is in bed all the time," a source told PEOPLE at the time, "usually four days out of the week. Hung over, she lays in bed; she's depressed, she just hangs out."
Ending Her EngagementIn November 2011, Locklear and fiancé Jack Wagner announced they had ended their engagement. One of their sticking points may be the fact he is sober and she is not, according to the ET report.
Wagner attributed it to bad timing, though, telling PEOPLE in late November, "We just found it impossible to combine our families. She has a life with [her 14-year-old daughter] Ava; I have a life with my two boys. It's not realistic in the near future to meld the two families."
"We took the pressure off and said, 'Let's just love each other the way we are,' " he said at the time.
But Locklear's parents maintain their daughter is doing well.
"She is in no danger, and she's going to be just fine," Bill and Diane Locklear said in a statement issued by Los Robles Hospital & Medical Center on Friday.
Reporting by ELAINE ARADILLAS