But Scott's family is disputing that report, says Los Angeles Coroner Chief Craig Harvey.
"According to family spokespersons, the information concerning brain cancer or an inoperable brain tumor in Mr. Scott is incorrect," he says.
So far, the coroner has not announced any findings regarding Scott's medical condition.
Scott, whose box-office hits included Top Gun, Days of Thunder and Beverly Hills Cop II, died Sunday after jumping from a bridge in Los Angeles Harbor. His body was recovered from the water four hours later.
Witnesses told authorities that at around 12:35 p.m., the filmmaker left his parked Toyota Prius on the Vincent Thomas Bridge in the city of San Pedro, scaled an 8- to 10-ft.-high fence and then leapt without hesitation.
A note with contact information was left in the vehicle, reported the Los Angeles Times, which also said a suicide note was located in Scott's office.
Scott leaves behind twin sons with his wife, actress Donna Scott (formerly Wilson), who appeared in Days of Thunder. Another survivor is his brother, fellow producer-director (Alien, Gladiator) and business partner Ridley Scott, 74.