The band's lead singer Ryan Tedder wrote the song, drawing on recordings of heartbeats of children in remote villages of Malawi and Guatemala for inspiration, and the video features never-before-seen footage of his visit there.
Tedder went to see some of Save The Children's programs, focusing on improving the health and nutrition of children and their families.
"As soon as we heard about the Every Beat Matters campaign, we knew we wanted to be involved," Tedder tells PEOPLE. "My trip to Guatemala showed me first-hand what Save the Children does for kids around the world. It was a special experience."
The Every Beat Matters campaign aims to make basic lifesaving health care available to children around the world so that millions more survive.
People can learn more and get updates about the campaign by liking the Every Beat Matters page on Facebook or by visiting www.EveryBeatMatters.org.