Jane Henson Dies of Cancer

Jane Henson Dead; Jim Henson's Wife
Jane Henson, with Kermit the Frog and the gang, in 2010
Mark Wilson/Getty

04/02/2013 AT 07:45 PM EDT

Jim Henson's partner in marriage and Muppets has died.

Jane Henson died at age 78 Tuesday at her Connecticut home following a battle with cancer, according to the Jim Henson Co.

She and Henson met in a University of Maryland puppetry class in the mid-1950s, and they became creative and business partners in the development of the Muppets.

The Hensons married in 1959 and had five children: Lisa, Cheryl, Brian, John and Heather. The pair separated in 1986, and Jim Henson died in 1990.

In 1992, Mrs. Henson created and funded The Jim Henson Legacy to preserve his artistic contributions.
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