The Emmy-winning actress's CBS show The Good Wife "ripped its title from the headlines when Silda Spitzer was standing right behind her husband" during the prostitution scandal, Margulies told PEOPLE on Tuesday.
With her character "loosely based" on Silda and other political wives who have stood by their husbands, Margulies says, "The headlines are now imitating us because both of these politicians – Spitzer and Weiner – have gotten back into the game of politics. And now newspapers are saying, 'Huma, take some advice from Alicia Florrick. Go back to work, don't read the papers.' "
But having played Alicia for so long on the show – the fifth season premieres Sept. 29 – the actress, says, "I have no judgment."
"Every woman has to do what feels best for her in that moment," she continues, "and I don't think anyone in that moment knows what the best situation to do is. I think it's called survival."
Adds Margulies, "Watching Huma [Abedin] on the podium, standing there next to her husband and saying she was going to stand by her man, I only had compassion and empathy for her, and felt like none of us know what she's going to do yet."