Briana, who works as Kaley's personal assistant, won over coach Christina Aguilera easily as she sang Lady Gaga's hit "You and I," earning kudos for her raw talent and power.
"You held those notes out really strong. You made me really happy," Aguilera told her, handily earning Cuoco's trust over competitor Cee Lo Green.
"Girl power!" Cuoco screamed as she picked Aguilera as coach.
Said proud sister Kaley, teary-eyed: "She's always put herself on the back burner for everyone else. There is no one who deserves this more." Watch Briana's audition below.
Only time will tell if Adam Levine got one over on Blake Shelton by picking a strong male country singer who had the nerve to audition with a Shelton hit.
Tyler Golden / NBC
Statuesque and model-pretty Monika Leigh, 28, of Boulder, Colo., picked a bluesy classic, B.B. King's "The Thrill Is Gone," and her effortless and nuanced version was a hit, turning all three male coaches around in their chairs.
"These guys are gonna have a bloodbath over you," Aguilera joked.
"I want to build my team around you," Shelton urged, and his charm offensive worked. "There's just something that you have. It's star quality."
Shelton also earned a strong southern singer in Ray Boudreaux, 25, a single father from Lafayette, La., whose soulful version of Bill Withers's "Use Me" belied his clean-cut image.
"You have an epically cool voice!" Levine told Boudreaux. "Bill Withers is like a father to me," added Green. "You got it. I wanna win with you."
But Shelton won again. "I wanna keep him swampy," he said. "I want him to bring the bluesy Louisiana sound. We've never really had that happen. I want to be the first."
Former teen model Lina Gaudenzi, 23, of Miami, earned a spot on Team Christina after a solid and folksy performance of Fleetwood Mac's "Landslide," while 16-year-old Juhi of Nashville went to Team Cee Lo after a "strong" and "effortless" rendition of the late Amy Winehouse's "Mercy."
"I feel connected to you. You feel like a little sister," Green said.
Green also chose a teen heartthrob in the making in George Horga Jr., 19, of Portland, Ore., who had the ladies in the audience screaming with his version of Bruno Mars's "Treasure."
The show finished solidly with Preston Pohl, 26, of Hallettsville, Texas. A former guitarist for a Christian rock band, Pohl said most people didn't realize he could even sing when he began his career as a solo artist.
He tore up MGMT's "Electric Feel" with a sweet falsetto and soulful growl as he worked the stage like a veteran. Green, Levine and Shelton all took note, but Levine went all in to grab Pohl's attention.
"The conviction with which you sing, I believe you," he said, later adding: "I wanted that guy probably worse than I wanted anybody so far. That dude is crazy good."
Week two of the blind auditions continue Tuesday night.