10/12/2013 at 12:00 PM EDT
Meg Ryan is bringing her movie-star talents to the small screen.
The Sleepless in Seattle
actress, 51, is set to star and executive-produce a pilot for NBC, PEOPLE has confirmed.
According to the show's description, Ryan will play "a sunny, devoted and desperately non-confrontational" single mom who decides to return to work at her former publishing house, where she will be supervised by her 30-year-old former intern.
The actress was once one of Hollywood's most bankable stars but had traded the spotlight for a more private existence
in New York with her 8-year-old daughter, Daisy, and boyfriend John Mellencamp, 62.
In recent years, Ryan has had small roles on Showtime's Web Therapy
and HBO's Curb Your Enthusiasm
, but this will be the actress's first major starring role since 2008's The Women