Meg Ryan to Star in New TV Show
10/12/2013 AT 01:30 PM EDT
The Sleepless in Seattle actress, 51, is set to star and executive-produce a pilot for NBC, PEOPLE has confirmed.
According to the show's description, Ryan will play "a sunny, devoted and desperately non-confrontational" single mom who decides to return to work at her former publishing house, where she will be supervised by her 30-year-old former intern.
The actress was once one of Hollywood's most bankable stars but had traded the spotlight for a more private existence in New York with her 8-year-old daughter, Daisy, and boyfriend John Mellencamp, 62.
In recent years, Ryan has had small roles on Showtime's Web Therapy and HBO's Curb Your Enthusiasm, but this will be the actress's first major starring role since 2008's The Women.