"If a woman has done a bit of work, you should never know," the TV personality tells New You in its spring issue.
"Women who do too much scare me. I'm glad it scares me. I was married to a plastic surgeon, so I've seen it all."
And the Dancing with the Stars co-host, 42, is a living example that women can get better with age.
Burke-Charvet says she feels healthier now than she did a decade ago, even after dealing with the threat of thyroid cancer.
"[My] 40s started out a little bit rough because there have been some life issues, but physically I feel better today than I did in my 30s," says Burke-Charvet, who is married to former Baywatch star David Charvet.
Justin Stephens for New You
Burke-Charvet's wisdom comes from experiencing some disappointments.
"I regret having a marriage that didn't work, because divorce is 'forever' for children," she says. "I regret that my two oldest daughters have to grow up knowing that sometimes a family falls apart. That's my heartbreaking life lesson. But I'm happy that they can see love now."
The mother of four says her children educate her every day.
"I've learned how to be flexible, and how to listen. I've learned how to accept people for who they are. They have different personalities – what works with one fails with another. I've learned to speak a different language with each of my children."