After a red carpet complete with costumed puppies and a cameo-filled intro by host Conan O'Brien, the MTV Movie Awards kicked off Sunday night – and just like the Golden Globes and the Oscars, the Dallas Buyers Club actor came away with a win.
Leto, 42, snagged a golden popcorn for best transformation. And as usual, the long-locked heartthrob couldn't resist flirting with presenter (and fellow Oscar winner) Lupita Nyong'o, 31.
"It's an award in itself to get that from her," he cooed.
Check out the full list of MTV Movie Awards winners and their best acceptance speech quotes below!
Best On-Screen Transformation: Jared Leto, Dallas Buyers Club
Leto spoke of the AIDS epidemic and his hope that the disease will be eradicated soon. "Love who you want to love and live how you wish to live, and never let anyone stop you from turning your dreams into reality," he said.
Best Comedic Performance: Jonah Hill, The Wolf of Wall Street
Hill, 30, thanked Leonardo DiCaprio and Martin Scorsese, but he also gave a shout-out to Judd Apatow and the cast of This Is the End. "I used to watch this awards show at home with all my friends, so first I want to thank all my friends," he said.
Best Villain: Mila Kunis, Oz the Great and Powerful
Pregnant Kunis, 30, cradled her golden popcorn. "Listen, you guys, you just made my 12-year-old-self dream come true," she said. "This is by far the coolest award and I just realized I was the only woman nominated and I won!"
Matt Sayles / Invision / AP
21 Jump Street costar Hill presented "Chan" with the award, joking "What's a more trailblazing experience than a f––– gorgeous man becoming a movie star?" Taking the jab in stride, Tatum, 33, said, "It's weird because 10 years ago I was sitting in front of my TV watching the show just like people at home right now, and I didn't have the faintest thought that I could be up here talking to y'all."
Best Kiss: Will Poulter, Jennifer Aniston and Emma Roberts, We're the Millers
Sadly, only Poulter, 21, was on hand to accept the award, meaning the long-standing tradition of winners kissing live couldn't continue – though he did joke about dating both costars. "On movie sets often actors hook up, it happens, you know," he said. "Me, Jen and Emma were so happy together. But you know, dating two women is hard. I don't know how anyone does it. But I am coping, I'm managing."
Matt Sayles / Invision / AP; Lester Cohen / WireImage
Bloom, 37, challenged fellow nominee Will Ferrell's Ron Burgundy to a fight and thanked the creatures his character Legolas battled. "I really want to thank the orcs, because inside each of those gnarly, dirty, sweaty latex suits was a stunt man or woman who nearly killed themselves every day on set just to make sure that we looked good," he said. "So this is for them."
Best Male Performance: Josh Hutcherson, The Hunger Games: Catching Fire
Hutcherson, 21, gamely responded to the attempts of presenters Leslie Mann, Cameron Diaz, Nicki Minaj and Kate Upton to objectify the nominees. "They're so tall," he said of the Other Woman actresses. "Me and Kate would never work. It'd be hard."
Best Female Performance: Jennifer Lawrence, The Hunger Games: Catching Fire
Diaz announced congratulations to the star, but Lawrence was not in attendance.
Movie of the Year: The Hunger Games: Catching Fire
Sam Claflin, 27, joined costar Hutcherson to accept the final golden popcorn, dedicating the win to their entire cast and crew and giving a special shout-out to the late Philip Seymour Hoffman. "I know that if Philip were here he would really think this was really cool, and to have him in our movies was one of the coolest things in the world," Hutcherson said. "He's one of the actors I've looked up to my entire life, and we think about him every day on set. So wherever he is, this definitely goes out to him as well."
Generation Award: Mark Wahlberg
Wahlberg, 42, gave a speech that was full of expletives – and heart. "I'm a lucky guy in so many ways, to have worked with so many talented people, to have gone from literally being incarcerated to having a one-hit rap career to having an underwear modeling career," he quipped of his pre-Hollywood credentials.