Still looking to find his way after his unceremonious exit from "The West Wing" last season, Rob Lowe, whose NBC's drama "The Lyon's Den" quickly crashed and burned earlier this season, has been cast to star in the CBS drama pilot "Dr. Vegas," says the Hollywood Reporter.

His role will be that of Dr. George Rivers, an in-house physician at a casino. Variety reports that at least one other network sought the services of Lowe (who turns 40 on St. Patrick's Day), but CBS got to him first.

In other pilot casting news, according to the trade papers, Alex Desert has joined the ABC private-eye drama "Harry Green and Eugene"; John Cho has jumped into the NBC comedy pilot "The Men's Room"; the WB Network has found its "Prodigy" in Coby Arens ("Riding in Cars With Boys"), whose mom will be played by Stacy Edwards; John Patrick Stewart and Josie Davis are tagged to costar in ABC's untitled comedy pilot starring Jennifer Love Hewitt as a sports reporter and single mom; and Cameron Richardson and Brent Weber have been cast in FOX's drama pilot "Point Pleasant."

But wait, there's more: Spencer Breslin ("Dr. Seuss's The Cat in the Hat") will join CBS's "Center of the Universe," playing Miles. His costars will be Diedrich Bader, John Goodman and Jean Smart.