Tatum takes direction from Oscar-winning filmmaker Ron Howard in the Vince Vaughn comedy, The Dilemma, where the hunk has a steamy affair with Winona Ryder. "I really loved working with him," Ryder said of Tatum. "I'd hear the girls screaming when we were doing any outdoor scenes, and I don't know how he does it."
Tatum continues to make audiences swoon with The Vow, a romantic drama that pairs the star with Rachel McAdams. Inspired by a true story about a husband trying to win his wife back after she suffers memory loss, the film opens No. 1 at the box office, with more than $41 million in ticket sales.
Tatum costars opposite Jonah Hill in the movie version of the '80s TV series 21 Jump Street, which tops the box office with $35 million its opening weekend. "I called him up, not even knowing him, and he just said yes on the phone," Hill tells Details magazine of offering the role to Tatum. "That never happens. I'm in awe of the guy. I don't want to sound like a broken record, but Chan's the best."
In a film loosely based on his real-life experience as an exotic dancer, Tatum stars alongside Matthew McConaughey in Magic Mike, a risqué drama about a veteran stripper who takes an up-and-coming performer under his wing. "I really enjoyed performing. It was probably my first performing job ever," Tatum tells Movieline of his former profession. The film debuts at No. 2, earning $39.2 million during its opening weeekend.
After a banner year at the box office, the hunky actor is named PEOPLE's Sexiest Man Alive. "My first thought was, 'Y'all are messing with me,'" he says of scoring the title. And how did wife Jenna Dewan-Tatum react? "Yeah, she calls me [the Sexiest Man Alive] now," Tatum jokes.
The Tatums welcome their first child, daughter Everly, in London, where the actor is filming Jupiter Ascending. "Once the baby is born, I'll definitely do the diaper changing," he told PEOPLE earlier this year, with wife Jenna echoing her husband's commitment to Glamour magazine in April. "Channing has been great," she said. "He takes the route of no confrontation, just support, saying things like, 'Do whatever you want!'"
BIOGRAPHY (top to bottom): Kerry Hayes/Vow Productions; Sony; Warner Bros.; Janet Mayer/Splash News Online; Courtesy of the Dewan-Tatum Family