With age, the boyishly handsome blond – twice named PEOPLE's Sexiest Man, in 1995 and 2000 – just keeps getting hotter. Brad Pitt has handled his spilt from wife Jennifer Aniston with grace, is starring in the highly anticipated Mr. and Mrs. Smith with Angelina Jolie and still has time for charity: He recently helped organize a series of public service announcements for The One Campaign, targeting AIDS and poverty.