Fall TV's Sexiest Guys

Check out 13 small-screen hotties, including Desperate Housewives' James Denton and Kitchen Confidential's Bradley Cooper. By Serena Kappes with Devon Thomas

JARED PADALECKI

He pursued Rory on Gilmore Girls, and now he's chasing urban legends on the WB thriller Supernatural. But Padalecki, 23 – who met girlfriend Sandy McCoy on the set of the horror movie Cry_Wolf, out Sept. 20 – says his ultimate catch would be another actor with a taste for the otherworldly: "I'd love to work with Johnny Depp," he told Teen People. "He elevates the performance of anyone he works with."